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Its absorption is slow, as it uses mechanisms similar to those used by amino acids. Therefore, magnesium bisglycinate is the form most easily absorbed and utilized by the body to fulfill its physiological functions.
Griffonia simplicifolia: 5-hydroxytryptophan is the main active component of Griffonia simplicifolia seeds, which are considered a natural source of this amino acid and used in the treatment of numerous effects associated with Serotonin Deficiency Syndrome. It is the precursor of serotonin, a neurotransmitter that regulates mood and emotions.
5-HTP is also the precursor of melatonin, which is synthesized from serotonin. Administration of 5-HTP to patients with migraines, headaches, or tension headaches resulted in higher plasma levels and beta-endorphin mononuclear cells, which may provide an explanation for the analgesic effect of 5-HTP in patients with headaches. In general, serotonin regulates mood, sleep, sexual activity, appetite, circadian rhythm, neuroendocrine functions, body temperature, pain sensitivity, motor activity, and cognitive functions. Daily supplementation with L-5-hydroxytryptophan has extensive and profound applications in balancing CNS disorders, including sleep, memory, learning, and temperature and mood regulation. It also aids sexual behavior, cardiovascular function, muscle contractions, endocrine regulation, and depression.
GABA is considered the main inhibitory neurotransmitter in the central nervous system of adult mammals. It is released by GABAergic neurons and binds to specific receptors on other neurons. These receptor neurons then experience a decrease in neuronal conduction, causing inhibition of the nervous system. As a result, the person may experience feelings of: relaxation; concentration; sleep. On the other hand, low GABA release is associated with neurological disorders and mental illnesses, including epilepsy, anxiety and insomnia. For this reason, some over-the-counter medicationsControlled medications enhance the action of GABA in the nervous system. These include benzodiazepines, such as clonazepam, and barbiturates, such as phenobarbital. However, this isn't the only way to boost GABA's action; it can be stimulated by foods or dietary supplements.